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Factors modifying QTc prolongation during hypoglycaemia in clinical studies.
| Factors decreasing QTc interval prolongation | Beta-blockade Antecedent hypoglycaemia Diabetes duration (T1D) Cardiac autonomic neuropathy |
| Factors increasing QTc interval prolongation | Time in hypoglycaemia Rate of plasma glucose decline (affects the onset of QTc interval prolongation) |
T1D, type 1 diabetes; QTc, corrected QT interval.
