Table 4.
UICC stage I-II (n = 36) | UICC stage III-IV (n = 44) | |||
---|---|---|---|---|
Univariate β (S), p value | Multivariate β (S), p value | Univariate β (S), p value | Multivariate β (S), p value | |
Age | −1.0 (0.60), 0.09 | 0.1 (0.6), 0.81 | −1.1 (0.5), 0.03∗ | −1.2 (0.5), 0.02∗1 |
Gender | −9.6 (10.26), 0.4 | −4.9 (9.3), 0.61 | −9.9 (11.3), 0.4 | −2.7 (11.2), 0.81 |
Pain | 0.5 (0.12), 0.0003∗∗ | 0.5 (0.2), 0.03 ∗ 1 | 0.2 (0.15), 0.3 | 0.1 (0.2), 0.41 |
Low mood | 11.5 (4.3), 0.01∗ | 2.2 (5.5), 0.71 | 11.5 (4.2), 0.01∗ | 6.0 (6.2), 0.31 |
Global health | −0.5 (0.2), 0.03∗ | −0.3 (0.2), 0.222 | 0.2 (0.2), 0.3 | 0.4 (0.0.3), 0.133 |
General QOL | −0.4 (0.2), 0.04∗ | −0.2 (0.2), 0.322 | 0.1 (0.2), 0.6 | 0.2 (0.3), 0.533 |
Insomnia | 0.4 (0.1), 0.005∗∗ | 0.2 (0.1), 0.222 | −0.0002 (0.2), 1.0 | −0.1 (0.2), 0.633 |
Depression | 14.2 (5.8), 0.02∗ | −2.4 (8.5), 0.822 | 8.3 (6.2), 0.19 | 6.8 (6.0), 0.633 |
Anxiety | 10.9 (6.5), 0.1 | 4.8 (7.1), 0.522 | 12.3 (6.1), 0.05 | 8.0 (6.9), 0.333 |
Add-on VA | 12.5 (11.7), 0.3 | 10.2 (10.6), 0.32 | 24.3 (11.2), 0.04∗ | 23.0 (39.5), 0.23 |
Dyspnoea | 0.1 (0.15), 0.5 | −0.2 (0.2), 0.32 | 0.1 (0.15), 0.5 | 0.05 (0.2), 0.83 |
Appetite loss | 0.1 (0.14), 0.3 | −0.01 (0.1), 0.92 | 0.001 (0.15), 1.0 | −0.02 (0.1), 0.93 |
Stress | 9.6 (5.3), 0.08 | −1.5 (6.1), 0.82 | 8.7 (6.4), 0.2 | 7.5 (7.1), 0.33 |
Association factors for the outcome: financial difficulties, EORTC QLQ-C30 questionnaire, version 3.0. univariate and multivariate linear regression modelling, QOL, quality of life, β = estimate, and S = error; 1Adjusted for age, gender, pain, and low mood; 2Adjusted for age, pain, and low mood; 3Adjusted for age and low mood; add-on VA, additional Viscum album L. extracts; ∗p < 0.05; ∗∗p ≤ 0.005.