Table 1.
Patients' characteristics.
| Characteristica | Seizure (N = 13) | IIC (N = 22) | Control (N = 38) | p-value (seizure/IIC) |
|---|---|---|---|---|
| Age, mean (SD), y | 58 (11) | 62 (15) | 49 (13) | 0.029/0.004** |
| Female | 8 (61.5%) | 14 (63.6%) | 27 (71.1%) | 0.730/0.577 |
| HH on admission | 0.701/0.744 | |||
| 1–3 | 3 (23.1%) | 5 (22.7%) | 7 (18.4%) | |
| 4–5 | 10 (76.9%) | 17 (77.3%) | 31 (81.6%) | |
| MFS | 0.311/0.148 | |||
| 0–2 | 0 (0%) | 0 (0%) | 5 (13.2%) | |
| 3–4 | 13 (100%) | 22 (100%) | 33 (86.8%) | |
| WFNS | 0.352/0.449 | |||
| 1–3 | 3 (23.1%) | 4 (18.2%) | 4 (10.5%) | |
| 4–5 | 10 (76.9%) | 18 (81.8%) | 34 (86.8%) | |
| GCS on presentation | 0.145/0.191 | |||
| 3–8 | 10 (76.9%) | 17 (77.3%) | 26 (68.4%) | |
| 9–12 | 0 (0%) | 1 (4.6%) | 8 (21.1%) | |
| 13–15 | 3 (23.1%) | 4 (18.2%) | 4 (10.5%) | |
| History of smoking | 7 (53.8%) | 9 (40.9%) | 20 (52.6%) | 1/0.431 |
| History of anticonvulsants use | 0 (0%) | 1 (4.5%) | 0 (0%) | 0.156/0.452 |
| History of seizure | 0 (0%) | 0 (0%) | 0 (0%) | 0.255/0.367 |
| Pressor use | 8/10 (80%) | 17/20 (85%) | 27/33 (82%) | 0.897/0.765 |
| History of HTN | 7 (53.8%) | 13 (59.1%) | 10 (26.3%) | 0.023/0.008 |
| History of DM | 4 (30.8%) | 4 (18.2%) | 3 (7.9%) | 0.019/0.143 |
| History of liver disease | 1 (7.7%) | 1 (4.5%) | 0 (0%) | 0.061/0.131 |
| History of kidney disease | 0 (0%) | 0 (0%) | 0 (0%) | 0.255/0.367 |
| IVH | 13 (100%) | 19 (86.4%) | 31 (81.6%) | 0.169/0.732 |
| Cerebral edema | 11 (84.6%) | 20 (90.9%) | 36 (94.7%) | 0.266/0.619 |
| Hemi-craniectomy | 1 (7.7%) | 1 (4.5%) | 6 (15.8%) | 0.662/0.246 |
| Hydrocephalus | 11 (84.6%) | 19 (86.4%) | 33 (86.8%) | 1/1 |
| Pulmonary edema | 4 (30.8%) | 9 (40.9%) | 17 (44.7%) | 0.518/0.794 |
| DCI | 5 (38.5%) | 8 (36.4%) | 16 (42.1%) | 1/0.787 |
| Disposition at ICU discharge | 0.010/0.143 | |||
| Home/acute rehab facility | 5 (38.5%) | 6 (27.3%) | 14 (36.8%) | |
| SNF | 8 (61.5%) | 10 (45.5%) | 9 (23.7%) | |
| Hospital | 0 (0.0%) | 22 (9.1%) | 1 (2.6%) | |
| Expired | 0 (0.0%) | 4 (18.2%) | 14 (36.8%) | |
| MRS at 3 months | 0.712/0.859 | |||
| 0–2 | 1 (7.7%) | 2 (9.1%) | 6 (15.8%) | |
| 3–6 | 10 (76.9%) | 15 (68.2%) | 23 (60.5%) | |
| Follow-up unavailable | 2 (15.4%) | 5 (22.7%) | 9 (23.7%) | |
| MRS at 12 months | 0.691 /0.587 | |||
| 0–2 | 2 (15.4%) | 4 (18.2%) | 6 (15.8%) | |
| 3–6 | 8 (61.5%) | 13 (59.1%) | 18 (47.4%) | |
| Follow-up unavailable | 3 (23.1%) | 5 (22.7%) | 14 (36.8%) | |
| LOS, mean (SD), d | 36.2 (15.5) | 28.8 (16.0) | 22.5 (12.7) | 0.006/0.144 |
IIC; ictal-interictal continuum; SD; standard deviation; HH; Hunt and Hess scale; MFS; Modified Fisher Scale; WFNS; World Federation of Neurosurgical Societies score; GCS; Glasgow Coma Scale; HTN; hypertension; DM; diabetes mellitus; IVH; intraventricular hemorrhage; DCI; delayed cerebral ischemia; SNF; skilled nursing facility; MRS; Modified Rankin Scale; LOS; length of hospital stay.
a
Data are presented as number (%) unless otherwise specified.
**
First p value is for seizure vs. control comparison, second p value is for IIC vs. control comparison. Significant differences (p > 0.05) are in bold.