. Author manuscript; available in PMC: 2021 Apr 1.

Published in final edited form as: J Perianesth Nurs. 2020 Jan 16;35(2):112–119. doi: 10.1016/j.jopan.2019.08.011

Table 2.

Summary of Common Atypical Antidepressant Drug Classifications

Drug Classification	Drug Example(s)

Serotonin-norepinephrine reuptake inhibitors (SNRI)	Venlafaxine Desvenlafaxine Duloxetine
Norepinephrine-dopamine reuptake inhibitors	Bupropion
Serotonin receptor antagonist with serotonin reuptake inhibition	Trazadone Nefazodone Vortioxetine
Noradrenergic alpha-2 receptor antagonists with 5-HT_2&3 antagonism	Mirtazapine
Atypical antipsychotics	Quetipine Risperidone Lurasidone Aripiprazole
N-methyl-D-aspartate glutamatergic blocker	Ketamine Esketamine

Note. This table shows a summary of different classifications of atypical antidepressants with example drugs. Only drug classifications approved by the Food and Drug Administration in the United States are included.