Fig. 2.

The ACCC group achieved early mature hyaline cartilage regeneration. a T2-weight spin-echo MRI with fat suppression in the sagittal plane and the coronal plane for each group at 6 months (6 m) and 9 months (9 m). Arrows indicate the defect region. b The scores were derived for five groups using the International Cartilage Repair Society (ICRS) Whole-Organ MRI Score (ICRS-WORMS) of the knee in OA. WORMS indicates the average score of the whole knee at 6 months (6 m) and 9 months (9 m). WORMS-MA, WORMS-Marrow abnormality: WORMS-BA, WORMS-bone attrition; WORMS-CA, WORMS-cartilage; T test was used for the data analysis and all data are expressed as the mean ± standard deviation (n = 6). Black circle, black square, black triangle and black star indicate significant differences between the ACCC group and the BC, AC, ACAC, and ACWJ groups, respectively. P < 0.05 indicates a statistically significant difference