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. 2020 May 19;20:447. doi: 10.1186/s12885-020-06816-2

Table 2.

Definitions and distributions of the eight quantitative volumetric, kinetic, and clinical variables used in this investigation

Variable used for Investigation Definition Male Female
Mean Median Range Mean Median Range

Age

(years)

Age of patient on date of diagnosis 57.58 58 12–95 58.41 60.5 9–96

T1Gd Radius

(mm)

Combined volume of the central non-enhancing necrotic region and surrounding enhanced region of tumor in a pre-tx T1Gd MR image (converted to a spherically- equivalent radius) 19.52 20.10 3.04–33.61 19.27 18.99 4.61–35.08
Necrosis Radius (mm) Volume of non-enhancing central necrotic region in a pre-tx T1Gd MR image (converted to a spherically- equivalent radius) 11.39 11.69 0.00–26.54 11.37 11.33 0.00–27.06
Contrast- enhancing (CE) thickness (mm) Average linear thickness of the contrast-enhancing region in a pre-tx T1Gd MR image (calculated as the difference between the T1Gd radius and the necrosis radius) 8.16 7.85 2.55–18.94 7.89 7.59 0.32–23.26
T2 /FLAIR radius (mm) Volume of the pre-tx T2 or T2-FLAIR MR image (converted to a spherically- equivalent radius) 27.11 28.31 9.94–39.55 26.98 27.86 9.99–42.81
PIHNA D (mm2/year) Net tumor cell diffuse invasion rate 32.34 28.99 1.45–145.3 36.25 23.03 0.37–289.9
PIHNA ϱ (year −1) Net tumor cell proliferation rate 65.88 18.25 1.83–1825 82.40 18.25 1.83–1825
PI D/ϱ (mm2) Relative tumor invasiveness 2.19 1.65 0.0034–10.26 2.12 1.28 0.0034–10.70