Table 2.
Laboratory data at the time of acute exacerbation in patients with IPF and CPFE-UIP
| Parameter | Patients with IPF (n = 41) |
Patients with CPFE (n = 21) |
p-value |
|---|---|---|---|
| WBC count (/mm3) | 10,030 (8620–12,500) | 88,810 (6460–9320) | 0.0096 |
| CRP (mg/dL) | 5.5 (2.4–10.7) | 5.85 (2.68–7.15) | 0.466 |
| LDH (IU/L) | 352 (261–453) | 289 (263–349) | 0.151 |
| KL-6 (U/mL) | 1596 (1225–2525) | 966 (429–1310) | < 0.001 |
| P/F ratio (Torr) | 204 (148–277) | 204 (130–261) | 0.417 |
| TR-PG (mmHg) | 38.0 (33.0–48.1) (n = 5) | 27.8 (25.4–55.0) (n = 7) | 0.871 |
|
CT pattern: peripheral or multifocal/diffuse |
27/14 (65.9%/34.1%) | 17/4 (89.0%/ 19.0%) | 0.345 |
The data are expressed as median (interquartile range) or number (percentage)
IPF idiopathic pulmonary fibrosis, CPFE combined pulmonary fibrosis and emphysema, WBC white blood cell, CRP C-reactive protein, LDH lactate dehydrogenase, KL-6 Krebs von den Lungen-6, P/F ratio ratio of partial pressure arterial oxygen to fraction of inspired oxygen (PaO2/FiO2), TR-PG transtricuspid pressure gradient, CT computed tomography