Table 4.
Comparative analyses of single ANCA test vs. combinational tests for ANCA/ASCA in the diagnosis of UC
Antibody/disease | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) |
---|---|---|---|---|
ANCA+/UC | 61.90 | 91.45 | 83.33 | 77.65 |
ANCA+/ASCA−/UC | 55.24 | 94.08 | 86.57 | 75.26 |
ASCA+/disease control group | 5.77 | 83.90 | 8.33 | 77.83 |
ASCA+/ANCA−/disease control group | 3.85 | 88.78 | 8.00 | 78.45 |
More than one positive test of ASCA-IgG and ASCA-IgA subtypes was regarded positive; two negative tests of the subtypes were regarded negative