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. 2020 May 20;16:37. doi: 10.1186/s13223-020-00433-1

Table 4.

Comparative analyses of single ANCA test vs. combinational tests for ANCA/ASCA in the diagnosis of UC

Antibody/disease Sensitivity (%) Specificity (%) Positive predictive value (%) Negative predictive value (%)
ANCA+/UC 61.90 91.45 83.33 77.65
ANCA+/ASCA/UC 55.24 94.08 86.57 75.26
ASCA+/disease control group 5.77 83.90 8.33 77.83
ASCA+/ANCA/disease control group 3.85 88.78 8.00 78.45

More than one positive test of ASCA-IgG and ASCA-IgA subtypes was regarded positive; two negative tests of the subtypes were regarded negative