Table 2.

Basic features of studies for diagnosis analysis

				Sample size				Diagnosis power
Study	Year	CircRNA	Cancer Type	case	control	Method	Regulation	Sen.	Spe.	AUC.
Ji et al. [16]	2018	circ_0001649	CRC	64	64	qRT-PCR	downregulated	0.828	0.781	0.857
Li et al. [19]	2018	circITGA7	CRC	69	48	qRT-PCR	downregulated	0.928	0.667	0.879
Wang et al. [24]	2017	circ_0000567	CRC	102	102	qRT-PCR	downregulated	0.833	0.765	0.865
Zhuo et al. [28]	2017	circ_0003906	CRC	122	40	qRT-PCR	downregulated	0.803	0.725	0.818
Ruan et al. [22]	2019	circ_0002138	CRC	35	35	qRT-PCR	downregulated	0.629	0.743	0.725
Wang et al. [32]	2015	circ_001988	CRC	31	31	qRT-PCR	downregulated	0.680	0.730	0.788
Li et al. [18]	2018	circ_0000711	CRC	101	101	qRT-PCR	downregulated	0.910	0.58	0.810

AUC Area under the ROC curve; qRT-PCR Quantitative real-time polymerase chain reaction; Sen Sensitivity; Spe. Specificity; CRC Colorectal cancer