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. 2020 May 20;36:14. doi: 10.1186/s42826-020-00045-1

Table 3.

Large cohorts of PDX consortiums

Organization Cancer types No. of models Genome data Distribution Web site
EurOPDX

EuroPDX consortium

(16 academic institutions)

30 1924 Gene mutations Available (Trans-national access or collaboration) https://www.europdx.eu/
NCI Patient-Derived Models Repository (PDMR) National Cancer Institute, USA 65 2925 OncoKB cancer panel, whole exome sequencing, RNA sequencing Available https://pdmr.cancer.gov/
Public Repository of Xenografts (PRoXe) Weinstock Laboratory Leukemia, lymphoma 157 Targeted exome sequencing (205 gene), RNA sequencing Available https://www.proxe.org/
The Jackson Laboratory PDX cohort The Jackson Laboratory 35 400+ Targeted exome sequencing, whole exome sequencing, RNA sequencing Available https://www.jax.org/jax-mice-and-services/in-vivo-pharmacology/oncology-services/pdx-tumors
Novartis Institutes for Biomedical Research PDX Encyclopedia (NIBR PDXE) Norvatis 16 1075 Whole exome sequencing, SNP array, RNA sequencing Not available https://www.nature.com/articles/nm.3954