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. 2020 May 20;18:51. doi: 10.1186/s12958-020-00612-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Knockdown of hsa_circ_0005243 inhibits cell migration. a An in vitro transwell assay showed a significant decrease in the migration ability of trophoblast cells following knockdown of hsa_circ_0005243, as evidenced by a decrease in migratory cell numbers. b. The number of migrated cells was counted for each group. c A wound-healing assay revealed a significant difference in migration distance before and after hsa_circ_0005243 knockdown. d The migratory distance was calculated 24 h after transfection. Data are presented as the mean ± SD, **p < 0.01