Figure 6.

Representative sections of lateral tail vein-injected mice 10 days after injection. The histological sections were stained with hematoxylin and eosin. (a) Moderate perivascular cellular infiltration (▴) with predominant lymphocytes and fewer neutrophilic granulocytes and plasma cells after injection of NaCl into the lateral tail vein (★). (b) Milder inflammatory infiltration (▸) in the connective tissue near the lateral tail vein (★) of a mouse after injection with doxorubicin. (c) Skeletal muscle bundles in proximity to the lateral tail vein (★) with a multifocal mild increase of endomysial connective tissue, as well as mild endomysial inflammatory infiltration and loss of multiple myofibers (▸) 10 days after doxorubicin injection. Scale bars: (a) 50 µm; (b), (c) 100 µm.