Table 3.

Correlation between carotid-femoral pulse wave velocity levels and clinical variables among the 205 chronic kidney disease patients

	Log-cfPWV (m/s)
	Univariate			Multivariate
Variables	r	P value		Beta	Adjusted R2 change	P value
Female	−0.123	0.080		–	–	–
Diabetes mellitus	0.203	0.003*		0.157	0.021	0.008*
Hypertension	0.058	0.411		–	–	–
Glomerulonephritis	−0.107	0.127		–	–	–
Age (years)	0.353	< 0.001*		0.308	0.098	< 0.001*
Height (cm)	0.035	0.618		–	–	–
Body weight (kg)	0.106	0.130		–	–	–
Body mass index (kg/m2)	0.105	0.135		–	–	–
Waist circumference (cm)	0.249	< 0.001*		–	–	–
Body fat mass (%)	0.081	0.249		–	–	–
SBP (mmHg)	0.392	< 0.001*		0.352	0.150	< 0.001*
DBP (mmHg)	0.156	0.026*		–	–	–
TCH (mmol/l)	−0.041	0.560		–	–	–
Log-Triglyceride (mmol/l)	0.084	0.233		–	–	–
LDL-C (mmol/l)	−0.085	0.223		–	–	–
Log-Glucose (mmol/l)	0.112	0.111		–	–	–
Log-BUN (mmol/l)	0.086	0.222		–	–	–
Log-Creatinine (µmol/l)	0.106	0.129		–	–	–
eGFR (ml/min)	−0.184	0.008*		–	–	–
Log-Calcium (mmol/l)	0.069	0.322		–	–	–
Phosphorus (mmol/l)	−0.052	0.459		–	–	–
Log-Leptin (ng/ml)	0.237	0.001*		0.192	0.042	0.001*

Data of carotid–femoral pulse wave velocity, triglyceride, glucose, BUN, creatinine, calcium, and leptin levels showed skewed distribution and therefore were log-transformed before analysis.

Analysis of data was done using the univariate linear regression analyses or multivariate stepwise linear regression analysis (adapted factors were diabetes mellitus, age, waist circumference, SBP, DBP, eGFR, and log-leptin).

cfPWV, carotid–femoral pulse wave velocity; SBP, systolic blood pressure; DBP, diastolic blood pressure; TCH, total cholesterol; LDL-C, low-density lipoprotein cholesterol; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate.

*P < 0.05 was considered statistically significant.