Figure 1. sIL-2R CSF/serum quotient diagrams.

Q_sIL-2R values were plotted against Q_Alb values of 115 patients (116 samples) from patients with NINDs (gray dots). The black line represents the linear regression line, and the red dotted line the upper 99% prediction band, indicating the area in which 99% of all data points from patients with NINDs are expected to fall. Values above the 99% prediction band were considered to indicate an intrathecal sIL-2R synthesis. Q_sIL-2R/Q_Alb values from the different disease groups analyzed in this study were subsequently added to the sIL-2R CSF/serum quotient diagram (blue diamonds). The numbers beneath the plot titles indicate the number of samples above the 99% prediction band, i.e., the number of samples with an intrathecal sIL-2R synthesis, among all analyzed samples. Note that in this evaluation, only samples with Q_Alb values within the Q_Alb reference range of patients with NINDs were included. Also, note that the x- and y-axis scales had to be expanded in some disease groups to accommodate highly elevated Q_sIL-2R and Q_Alb values. GBS = Guillain-Barré syndrome; NINDs = noninflammatory neurologic diseases; Q_Alb = CSF/serum albumin quotient; Q_sIL-2R = CSF/serum soluble interleukin-2 receptor quotient; sIL-2R = soluble interleukin-2 receptor.