TABLE 1.

Proteins associated with S100A8 in the network.

Protein ID	Name	Polycystic Ovary Syndrome (PCOS) relative function
MMP9	Matrix Metallopeptidase 9	Proteolytic activity on the extracellular matrix (ECM) and involved in leukocyte migration
RETN	Resistin	Promotes chemotaxis in myeloid cells
CTSS	Cathepsin S	Endo protease involved in the removal of unwanted proteins
S100A9	S100 Calcium Binding Protein A9	Potent amplifier of inflammation as well as in cancer development and tumor spread
NCF2	Neutrophil Cytosolic Factor 2	Involved in superoxide generation
MPO	Myeloperoxidase	Produce hypochlorous acid and other toxic intermediates which enhance PMN microbicidal activity
ALB	Albumin	Regulates blood plasma colloid osmotic pressure and acts as a carrier protein for hormones, fatty acids, metabolites, and exogenous drugs
BECN1	Beclin 1	Mediates vesicle-trafficking processes, tumorigenesis, neurodegeneration, and apoptosis
TP53	Tumor Protein P53	Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression
GRB2	Growth Factor Receptor Bound Protein 2	Adapter protein involved in the Ras signaling pathway