Table 1.

Characteristics of patients treated with rescue systemic fibrinolysis.

Patient	1	2	3–1	3–2	4	5
Age (years)	67	41	63	63	55	46
Sex	Male	Male	Male	Male	Male	Male
BMI (kg/m²)	26.2	25.8	27.2	27.2	20.7	24.3
SAPS II	26	22	47	47	28	31
Invasive MV	No	Yes	Yes	Yes	Yes	Yes
Number of PP sessions	0	1	1	1	1	4
PaO₂/FiO₂ ratio (mmHg)	80	85	80	91	94	62
PaCO₂ (mmHg)	36	56	76	46	53	53
Respiratory system compliance (ml/cmH₂O)	NA	33	30	16	17	10
Driving pressure (cmH₂O)	NA	12	15	25	23	16
NE dose (μg/kg/min)	2.94	0.22	1.06	2.05	0.25	3.46
VV-ECMO	No	No	No	No	No	Yes
Antithrombotic regimen	Curative LMWH	Preventive LMWH	Curative LMWH	Curative UFH	Curative LMWH	Curative UFH
D-Dimer (ng/ml)	2281	NA	4208	4208	7794	9943
PR (%)	64	67	77	71	70	80
Platelet count (Giga/l)	355	194	391	403	199	176
Fibrinogen (g/l)	7.7	8.4	7.0	6.4	6.5	4.8
Reason for fibrinolysis	CA	CA	Shock	Shock	Shock	Shock
Imaging	ACP	ACP + CFV thrombosis	ACP	ACP	ACP	ACP
Complications	–	–	–	–	Femoral hemorrhage: 8 RBC transfused	Jugular + femoral hemorrhage: 3 RBC transfused
Immediate effect	No ROSC	No ROSC	60% NE decrease in 1 h	Persistent shock	Persistent shock	80% NE decrease in 3 h
Vital status	Death	Death	Death 3 days later	Death 2 days later	Death 3 days later	Alive at 7 days

All clinical characteristics are reported before initiation of rescue therapy.

Abbreviations: ACP: acute cor pulmonale, BMI: body mass index, CA: cardiac arrest, CFV: common femoral vein, h: hour, LMWH: low molecular weight heparin, MV: mechanical ventilation, NA: not applied, NE: norepinephrine, PC: platelet concentrate, PE: pulmonary embolism, PP: prone position, PR: prothrombin ratio, RBC: red blood cell, ROSC: return of spontaneous circulation, SAPS II: simplified acute physiology score II, UFH: unfractioned heparin, VV-ECMO: veno-venous extracorporeal membrane oxygenation.