Table 1.

Results for multivariate models predicting ACE2 and TMPRSS2 expression

Model	Predictor		Partial R2 (%)	Effect Size		t-test
	Variable	Ref.		Coeff.	SE	t	p-value
ACE2	Age	n/a	1.03	−0.032	0.009	−3.64	0.000300
	Interferon Status	Low	17.09	1.301	0.088	14.78	6.50e-43
	Type 2 Inflammation	Low	24.44	−1.001	0.057	−17.68	1.58e-57
	Sex	Male	0.14	0.075	0.056	1.33	0.185421
	Asthma	Healthy	0.58	−0.160	0.059	−2.73	0.006415
	rs181603331 (G>T)	G/G	1.20	−0.635	0.162	−3.92	0.000097
TMPRSS2	Age	n/a	0.07	−0.008	0.010	−0.88	0.380112
	Interferon Status	Low	0.07	0.087	0.098	0.88	0.378731
	Type 2 Inflammation	Low	33.24	1.177	0.063	18.77	1.74e-63
	Sex	Male	0.02	−0.031	0.062	−0.50	0.616276
	Asthma	Healthy	<0.01	0.014	0.065	0.22	0.829301
	rs1475908 (G>A)	G/G	0.22	−0.082	0.054	−1.51	0.130251
	rs74659079 (C>T)	C/C	0.39	0.216	0.107	2.03	0.043151
	rs2838057 (A>C)	A/A	0.42	0.139	0.066	2.12	0.034678