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Sanguinarine (SG) shows a prominent inhibitory effect on LoVo cells in vitro. A, The chemical structure of SG. B, Effects of SG on cell proliferation in LoVo, SW480, and Caco‐2 cells were determined by MTT assay. Cells were treated with SG (0.39‐50 µM) for 48 hours. C, Effects of SG on colony formation in LoVo cells (200×). D, Quantification of the data represented in (C). Values are presented as mean ± SD. *P < .05, **P < .01, and ***P < .001 versus the control group
