Table 2:
Immunopathology of 167 PTLD cases in which pathology reports available
| Variable | EBV positive [N(%)] | EBV negative [N(%)] | p-value |
|---|---|---|---|
| Number of patients | 135 | 32 | |
| Morphologic Type | 0.188 | ||
| Monomorphic | 88 (65) | 21 (66) | |
| Polymorphic | 38 (28) | 6 (19) | |
| Missing | 9 ( 7) | 5 (16) | |
| Ki67 staining | 0.367 | ||
| 40–69 | 8 ( 6) | 2 ( 6) | |
| 70–79 | 8 ( 6) | 0 | |
| 80–89 | 12 ( 9) | 1 ( 3) | |
| ≥90 | 18 (13) | 7 (22) | |
| Missing | 89 (66) | 22 (69) | |
| Bcl6 staining | 0.438 | ||
| Positive | 14 (10) | 4 (13) | |
| Negative | 17 (13) | 1 ( 3) | |
| Not tested/Not reported | 104 (76) | 27 (84) | |
| Bcl2 staining | 0.655 | ||
| Positive | 27 (20) | 9 (28) | |
| Negative | 2 ( 1) | 0 | |
| Not tested/Not reported | 106 (78) | 23 (72) | |
| CD20 staining | 0.120 | ||
| Positive | 100 (74) | 19 (59) | |
| Negative | 3 ( 2) | 0 | |
| Not tested/Not reported | 32 (24) | 13 (41) | |
| CD30 staining | 0.469 | ||
| Positive | 34 (25) | 9 (28) | |
| Negative | 5 ( 4) | 0 | |
| Not tested/Not reported | 96 (71) | 23 (72) | |
| Pathology | 0.636 | ||
| PTLD | 91 (67) | 19 (59) | |
| DLBCL | 39 (29) | 12 (38) | |
| Others | 5 ( 4) | 1 ( 3) | |
| Subtype | 0.963 | ||
| DLBCL | 58 (43) | 15 (47) | |
| Polymorphic PTLD | 27 (20) | 6 (19) | |
| Burkitt | 2 ( 1) | 1 ( 3) | |
| PTLD NOS | 24 (18) | 5 (16) | |
| Plasmacytoid | 13 (10) | 3 ( 9) | |
| T-cell NOS | 2 ( 1) | 1 ( 3) | |
| Monomorphic PTLD | 2 ( 1) | 0 | |
| No morphology | 4 ( 3) | 0 | |
| Missing | 3 ( 2) | 1 ( 3) |