Table 1:
Baseline Characteristics
| Characteristic | Case (N=140) | Control (N=305) | Total (N=445) | |
|---|---|---|---|---|
| Age (at parent study entry) | Years, Median (IQR) | 46 (40–53) | 44 (39–50) | 45 (39–50) |
| Regimens (by parent study) | ACTG 384 / ACTG 388 | 39 (28%) | 84 (28%) | 123 (28%) |
| A5014 / A5095 / A5142 | 69 (49%) | 158 (52%) | 227 (51%) | |
| A5202 | 32 (23%) | 63 (21%) | 95 (21%) | |
| Sex | Male, N (%) | 118 (84%) | 258 (85%) | 376 (84%) |
| Female, N (%) | 22 (16%) | 47 (15%) | 69 (16%) | |
| Race/ethnicity | White Non-Hispanic, N (%) | 72 (51%) | 148 (49%) | 220 (49%) |
| Black Non-Hispanic, N (%) | 52 (37%) | 87 (29%) | 139 (31%) | |
| Hispanic, N (%) | 15 (11%) | 59 (19%) | 74 (17%) | |
| Others, N (%) | 1 (1%) | 11 (3%) | 12 (3%) | |
| Baseline CD4 | Cells/ul, Median (IQR) | 211 (89–341) | 222 (76–335) | 219 (77–336) |
| Baseline log10 HIV RNA | Copies/mL, Median (IQR) | 4.8 (4.4–5.3) | 4.8 (4.4–5.4) | 4.8 (4.4–5.4) |
| Chronic Hepatitis B/C | Yes, N (%) | 36 (26%) | 34 (11%) | 70 (16%) |
| Injection Drug Use | Yes, N (%) | 20 (14%) | 30 (10%) | 50 (11%) |
| Waist-to-hip Ratio | Median (IQR) | 0.92 (0.89–0.96) | 0.92 (0.88–0.97) | 0.92 (0.89–0.97) |
| History of Diabetes | Yes, N (%) | 11 (8%) | 15 (5%) | 26 (6%) |
| History of Hypertension | Yes, N (%) | 46 (33%) | 55 (18%) | 101 (23%) |
| Use of antihypertensive or lipid lowering agents | Yes, N (%) | 32 (23%) | 39 (13%) | 71 (16%) |
| Current or Past Smoker | Yes, N (%) | 105 (75%) | 168 (55%) | 273 (61%) |
| Family history of MI | Yes, N (%) | 30 (21%) | 45 (15%) | 75 (17%) |
IQR: interquartile range
See supplement for ACTG study details and regimens.