Table 1.

Optimization of Disaccharide 15

entry	donor/acceptor	scavenger	temp	yield (α-only)
1a	2:1	TTBP	rt	14%b
2a	2:1	TTBP	0 °C	44%b
3a	2:1	DTBMP	0 °C	11%b
4c	2:1	TTBP	0 °C	18%b
5d	1:2	TTBP	0 °C	47%b
6d	1:3	TTBP	0 °C	64%b
7d	1:3	TTBP	−10 °C	74%e
8d,f	1:3	TTBP	−10 °C	69%e

^aTCE/CH₂Cl₂ (2.7:1).

^bNMR yield, product identified in a complex with α,α-trehalose.

^cTCE/CH₂Cl₂/THF (6.5:1:3.2).

^dTCE/CH₂Cl₂ (1.6:1).

^eIsolated yield.

^f300 mg scale of 8.