Table 3. Studies demonstrating significant change in miR-148/152 expression in PE patients compared with healthy pregnant women.
| Study | Type of study | Type of PE | Time of collection | Tissue sample | Direction of change |
|---|---|---|---|---|---|
| miR-148a | |||||
| Zhao et al. 2014 [211] | Microarray | Severe LO | Delivery | Decidua derived MSCs | Down |
| Zhou et al. 2016 [26] | RNA seq and qPCR | Diagnosed | Delivery | Chorionic plate from quadrant and central portion in placenta disc | Up |
| miR-152 | |||||
| Zhu et al. 2009 [19] | Microarray and qPCR | Mild and severe | Delivery | Placenta villi | Up |
| Ura et al. 2014 [62] | Microarray | Severe | 12–14 weeks | Serum | Up |
| Jiang et al. 2015 [25] | Microarray | Severe | Delivery | 8 maternal and 8 fetal sites | Up |
LO, late onset; MSCs, mesenchymal stem cells; Time of collection designated ‘delivery’ if not stated in study.