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. 2020 Apr 27;134(8):1001–1025. doi: 10.1042/CS20200023

Table 3. Studies demonstrating significant change in miR-148/152 expression in PE patients compared with healthy pregnant women.

Study Type of study Type of PE Time of collection Tissue sample Direction of change
miR-148a
Zhao et al. 2014 [211] Microarray Severe LO Delivery Decidua derived MSCs Down
Zhou et al. 2016 [26] RNA seq and qPCR Diagnosed Delivery Chorionic plate from quadrant and central portion in placenta disc Up
miR-152
Zhu et al. 2009 [19] Microarray and qPCR Mild and severe Delivery Placenta villi Up
Ura et al. 2014 [62] Microarray Severe 12–14 weeks Serum Up
Jiang et al. 2015 [25] Microarray Severe Delivery 8 maternal and 8 fetal sites Up

LO, late onset; MSCs, mesenchymal stem cells; Time of collection designated ‘delivery’ if not stated in study.