Differential expression of mRNA, miRNA and protein across time and across tissue. a) The number of biomolecules declared differentially expressed between responders and non-responders at 10% FDR for each tissue, time point, and platform. The number of tests vary between platforms, mRNA (19304), miRNA (3632), protein (1129) b) Model metrics for random forests; we report mean (SD) predictive error and number of features retained after recursive feature elimination for each data platform and response type. Continuous response models were evaluated using root mean square error (RMSE), while categorical models were tuned with cross entropy loss. Asterisks denote the top performing data platform for each class of random forests.