Figure 7.

a: The mean number of S100-positive Schwann cells after surgery in experimental groups

** Difference between sham surgery and other groups, 30 days after surgery (P<0.001). ¥ Difference between ESM+DMSO group with ESM+lycopene and autograft groups, 90 days after surgery (P<0.01). Results are presented as mean±SEM. b: Immunohistochemical analysis of transverse sections of the regenerated nerve 90 days after surgery. (a) Sham surgery, (b) Autograft, (c) ESM+DMSO, and (d) ESM+lycopene. There was S100-positive Schwann cells. Regenerated nerve fibers including myelinated axons, Schwann cells and blood vessels were present all over the tissue (scale bar 20 µm). MF: micro fascicle, BV: blood vessel, M: macrophage, DMSO: Dimethyl sulfoxide, ESM: Egg shell membrane