. 2020 Apr;23(4):469–482. doi: 10.22038/ijbms.2020.39427.9349

Table 2.

Some potential targets of miRNAs in apoptotic and migration pathways

*microRNA*	*Potential target*	*Gene name*
21	*APAF1*	*Apoptotic peptidase activating factor 1*
	*ARHGAP24*	*Rho GTPase activating protein 24*
	*EGR3*	*early growth response 3*
	*MAP2K3*	*mitogen-activated protein kinase kinase 3*
	*MEGF9*	*multiple EGF-like-domains 9*
	*MYCL*	*v-myc avian myelocytomatosis viral oncogene lung carcinoma derived ho* mo *log*
	*PIK3R1*	*phosphoinositide-3-kinase, regulatory subunit 1 (alpha)*
	*RASA1*	*RAS p21 protein activator (GTPase activating protein) 1*
	*RGS7BP*	*regulator of G-protein signaling 7 binding protein*
	*SMAD7*	*SMAD family member 7*
	*TADA2A*	*transcriptional adaptor 2A*
	*TGFBI*	*transforming growth factor, beta-induced, 68kDa*
	*TP53*	tu mo *r protein p53*
*221*	*APAF1*	*Apoptotic peptidase activating factor 1*
	*BAG1*	*BCL2-associated athanogene*
	*CADM1*	*cell adhesion* mo *lecule 1*
	*CASP2*	*caspase 2, apoptosis-related cysteine peptidase*
	*CASP3*	*caspase 3, apoptosis-related cysteine peptidase*
	*CASP9*	*caspase 9, apoptosis-related cysteine peptidase*
	*CCNG1*	*cyclin G1*
	*CRTC1*	*CREB regulated transcription coactivator 1*
	*DAP*	*death-associated protein*
	*GPRIN2*	*G protein regulated inducer of neurite outgrowth 2*
	*GRAP*	*GRB2-related adaptor protein*
	*GRB2*	*growth factor receptor-bound protein 2*
.	*JAK2*	*Janus kinase 2*
	*NOTCH1*	*notch 1*
	*TAF13*	*TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa*
	*TP53AIP1*	tu mo *r protein p53 regulated apoptosis inducing protein 1*
*222*	*APAF1*	*Apoptotic peptidase activating factor 1*
	*CADM1*	*cell adhesion* mo *lecule 1*
	*CASP3*	*caspase 3, apoptosis-related cysteine peptidase*
	*CASP9*	*caspase 9, apoptosis-related cysteine peptidase*
	*CCNG2*	*cyclin G2*
	*CCPG1*	*cell cycle progression 1*
	*CD34*	*CD34* mo *lecule*
	*CDK1*	*cyclin-dependent kinase 1*
	*CREBBP*	*CREB binding protein*
	*DFFA*	*DNA fragmentation factor, 45kDa, alpha polypeptide*
	*FGFR1OP*	*FGFR1 oncogene partner*
	*GAB3*	*GRB2-associated binding protein 3*
	*GRK5*	*G protein-coupled receptor kinase 5*
	*MAD2L1*	*MAD2 mitotic arrest deficient-like 1 (yeast)*
	*MEGF11*	*multiple EGF-like-domains 11*
	*NOTCH2*	*notch 2*
	*NOX1*	*NADPH oxidase 1*
	*RASAL2*	*RAS protein activator like 2*
	*SERBP1*	*SERPINE1 mRNA binding protein 1*
	*SMAD2*	*SMAD family member 2*
	*TANK*	*TRAF family member-associated NFKB activator*
	*TP53INP1*	tu mo *r protein p53 inducible nuclear protein 1*
*155*	*BAG5*	*BCL2-associated athanogene 5*
	*DMTF1*	*cyclin D binding myb-like transcription factor 1*
	*E2F2*	*E2F transcription factor 2*
	*FGF9*	*fibroblast growth factor 9*
	*G3BP2*	*GTPase activating protein (SH3 domain) binding protein 2*
	*GAB3*	*GRB2-associated binding protein 3*
	*GDF6*	*growth differentiation factor 6*
	*KRAS*	*Kirsten rat sarcoma viral oncogene ho* mo *log*
	*KSR1*	*kinase suppressor of ras 1*
	*MARK2*	*MAP/microtubule affinity-regulating kinase 2*
	*PKIA*	*protein kinase (cAMP-dependent, catalytic) inhibitor alpha*
	*RBAK*	*RB-associated KRAB zinc finger*
	*SLA*	*Src-like-adaptor*
	*SMAD2*	*SMAD family member 2*
	*SOCS1*	*suppressor of cytokine signaling 1*
	*TAB2*	*TGF-beta activated kinase 1/MAP3K7 binding protein 2*
	*TAPT1*	*transmembrane anterior posterior transformation 1*
	*TBRG1*	*transforming growth factor beta regulator 1*
	*TCF4*	*transcription factor 4*
	*TCF7L2*	*transcription factor 7-like 2 (T-cell specific, HMG-box)*
	*TP53INP1*	tu mo *r protein p53 inducible nuclear protein 1*
	*TPD52*	tu mo *r protein D52*
	*TRAF3*	*TNF receptor-associated factor 3*
	*VEZF1*	*vascular endothelial zinc finger 1*
*126*	*AKT3*	*v-akt murine thy* mo *ma viral oncogene ho* mo *log 3*
	*ALDH1A1*	*aldehyde dehydrogenase 1 family, member A1*
	*ANGPT1*	*angiopoietin 1*
	*BAK1*	*BCL2-antagonist/killer 1*
	*BCL2*	*B-cell CLL/lymphoma 2*
	*CADM1*	*cell adhesion* mo *lecule 1*
	*CCNG1*	*cyclin G1*
	*CCNG2*	*cyclin G2*
	*CCPG1*	*cell cycle progression 1*
	*CREBBP*	*CREB binding protein*
	*DFFA*	*DNA fragmentation factor, 45kDa, alpha polypeptide*
	*MYCBP*	*MYC binding protein*
	*MYCT1*	*myc target 1*
	*NKAP*	*NFKB activating protein*
	*RASA1*	*RAS p21 protein activator (GTPase activating protein) 1*
	*RASAL2*	*RAS protein activator like 2*
	*RASEF*	*RAS and EF-hand domain containing*
	*RASGEF1B*	*RasGEF domain family, member 1B*
	*RGS1*	*regulator of G-protein signaling 1*
	*SERPINA10*	*serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10*
	*SERPINA5*	*serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5*
	*SMAD2*	*SMAD family member 2*
	*TAB2*	*TGF-beta activated kinase 1/MAP3K7 binding protein 2*
	*TAPBP*	*TAP binding protein (tapasin)*
	*TNIK*	*TRAF2 and NCK interacting kinase*
	*VEGFA*	*vascular endothelial growth factor A*
*34a*	*AKT3*	*adenylate kinase 3*
	*SERPINB5*	*Maspin (mammary serine protease inhibitor)*
	*BMP7*	*bone* mo *rphogenetic protein 7*
	*CD34*	*CD34* mo *lecule*
	*EGF*	*Epidermal growth factor*
	*ARHGAP26*	*Rho GTPase activating protein 26*
	*ARPP19*	*cAMP-regulated phosphoprotein, 19kDa*
	*BCL2*	*B-cell CLL/lymphoma 2*
	*CDC25A*	*cell division cycle 25A*
	*E2F3*	*E2F transcription factor 3*
	*FOSL1*	*FOS-like antigen 1*
	*GPR12*	*G protein-coupled receptor 12*
	*GREM2*	*gremlin 2, DAN family BMP antagonist*
	*MDM4*	*Mdm4 p53 binding protein ho* mo *log (* mo *use)*
	*NOTCH1*	*notch 1*
	*SMAD4*	*SMAD family member 4*
	*SOCS4*	*suppressor of cytokine signaling 4*
*Let7b*	*AKAP5*	*A kinase (PRKA) anchor protein 5*
	*AMER3*	*APC membrane recruitment protein 3*
	*ANGPTL2*	*angiopoietin-like 2*
	*CDCA8*	*cell division cycle associated 8*
	*E2F2*	*E2F transcription factor 2*
	*HBEGF*	*heparin-binding EGF-like growth factor*
	*MAP3K1*	*mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase*
	*MDM4*	*Mdm4 p53 binding protein ho* mo *log (* mo *use)*
	*RASGRP1*	*RAS guanyl releasing protein 1 (calcium and DAG-regulated)*
	*RASL10A*	*RAS-like, family 10, member A*
	*RGS16*	*regulator of G-protein signaling 16*
	*SMAD2*	*SMAD family member 2*
	*SOCS1*	*suppressor of cytokine signaling 1*
	*STK24*	*serine/thrseonine kinase 24*
	*SERPINA12*	*Serpin Family A Member 12*
	*SERPINB5*	*Maspin (mammary serine protease inhibitor)*
	*BMP7*	*bone* mo *rphogenetic protein 7*
	*CD34*	*CD34* mo *lecule*
	*EGF*	*Epidermal growth factor*