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The mRNA expression of GR, MR, CRF1R, and CRF2R in the hippocampus was detected by RT-PCR. GR mRNA, MR mRNA, CRF1R mRNA, and CRF2R mRNA were shown in a–d. Values were expressed as mean±SEM (##P<0.01 vs control group, *P<0.05, **P<0.01 vs SPS group, n=6). GR: glucocorticoid receptor; MR: mineralocorticoid receptor; CRF1R: corticotropin releasing factor 1 recaptor; CRF2R: corticotropin releasing factor 2 recaptor; SPS: single prolonged stress; PEF: paeoniflorin; PRX: paroxetine
