Table 4. Results of multiple regression analysis of the effect of metabolic syndrome score and its components on the levels of markers of endothelial dysfunction in adolescents.
Outcome variables | |||
---|---|---|---|
Independent variables | ICAM-1 | VCAM-1 b | |
Model 1a | cMets score | 5.58 (1.64)** | 0.0003 (0.01) |
Model 2 a | BMI, kg/m2 | 0.73 (1.71) | -0.01 (0.01) |
MAP, mmHg | 0.41 (0.60) | 0.002 (0.002) | |
Fasting glucose, mg/dL | 0.33 (0.74) | 0.003 (0.003) | |
TG, mg/dL | 0.12 (0.14) | -0.0002 (0.001) | |
HDL-c, mg/dL | -1.36 (0.53)* | -0.002 (0.002) |
Abbreviation: BMI, body mass index; MAP, mean arterial pressure; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; ICAM-1, intercellular adhesion molecule; VCAM-1, vascular cell adhesion molecule; cMets, continuous metabolic syndrome.
Results are coefficients with standard errors.
*p < 0.05,
**p < 0.01.
aCoefficients and p-values were obtained after adjustment for sex, age, monthly household income, parental history of hypertension, parental history of diabetes, weekly vigorous-intensity physical activity, TV viewing, secondhand smoking, eating breakfast, and total energy intake.
bVCAM-1 did not satisfy a normal distribution, and so was log transformed.