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. 2020 May 20;15(5):e0233054. doi: 10.1371/journal.pone.0233054

Fig 5. Pro-inflammatory cytokines in media and Extracellular Vesicles (EV) isolated from U937 (uninfected) and U1 (HIV-infected) macrophages treated with CSC long-term.

Fig 5

a. Concentration of IL-6 in media, EV, and percent of cytokine packaged in EV. b. Concentration of IL-1β in media, EV, and percent of cytokine packaged in EV. c. Concentration of TNF-α in media, EV, and percent of cytokine packaged in EV. *p<0.05, **p<0.001 compared to control; #p<0.05, ##p<0.001 compared to HIV. $p<0.05 and $ $p<0.001 compared to CSC. Bars represent data from n = 3 replicates. Statistical analysis performed: One-way ANOVA with Tukey’s Multiple comparison test.