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. 2020 May 17;10(5):e036465. doi: 10.1136/bmjopen-2019-036465

Table 2.

Standardised mortality ratios

Variable Groups SMR (95% CI)
All participants 2.24 (1.99 to 2.50)
Age group* 15–25 years 18.73 (0.37 to 37.09)
26–35 years 4.21 (1.29 to 7.13)
36–45 years 3.86 (2.28 to 5.44)
46–55 years 3.77 (2.90 to 4.74)
>55 years 1.86 (1.60 to 2.12)
Sex Male 1.69 (1.42 to 1.95)
Female 3.48 (2.90 to 4.06)
Ability level Mild ID 1.60 (1.27 to 1.92)
Moderate ID 2.10 (1.62 to 2.58)
Severe ID 2.78 (2.11 to 3.44)
Profound ID 4.14 (3.11 to 5.17)
Down syndrome No 1.93 (1.68 to 2.18)
Yes 5.28 (3.98 to 6.57)
Underlying causes of death grouped by ICD-10 chapter† Congenital malformations, deformations and chromosomal abnormalities 17.26 (10.75 to 23.78)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism 7.50 (-7.20 to 22.20)
Diseases of the circulatory system 5.55 (4.01 to 7.09)
Diseases of the digestive system 16.13 (8.23 to 24.04)
Diseases of the genitourinary system 3.65 (0.73 to 6.57)
Diseases of the musculoskeletal system and connective tissue 5.40 (-0.71 to 11.52)
Diseases of the nervous system 7.73 (5.13 to 10.32)
Diseases of the respiratory system 6.78 (5.02 to 8.54)
Diseases of the skin and subcutaneous tissue 2.75 (−2.64 to 8.15)
Endocrine, nutritional and metabolic diseases 3.43 (1.05 to 5.81)
External causes of morbidity and mobility 11.08 (3.40 to 18.76)
Infectious and parasitic diseases 8.93 (1.78 to 16.07)
Mental and behavioural disorders 12.64 (3.27 to 22.00)
Neoplasms 6.31 (4.19 to 8.43)
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified 19.51 (0.39 to 38.63)

*Data used for comparison with General Population (GG&C Health Board) provide data in 5-year age bands therefore 15+. Data on adults with ID are 16+.

†Negative Lower CI and wide CIs indicate low number of observed deaths in study population.

ICD-10, International Statistical Classification of Diseases and Related Health Problems, 10th Revision; ID, intellectual disabilities; SMR, standardised mortality ratios.