Table 4.

Underlying causes of death grouped by specific individual causes or related groups of causes, where cause of death is known

Causes	Participants with Down syndrome (n=57)	Participants without Down syndrome (n=205)
Aspiration/reflux/choking	<5	22 (10.8%)
Respiratory infection	<5	21 (10.3%)
Down syndrome	21 (36.8%)	<5
Other malignancy	<5	19 (9.3%)
Other condition	<5	17 (8.3%)
Epilepsies	<5	13 (6.4%)
Acute myocardial infarction	<5	13 (6.4%)
Gastrointestinal malignancy	<5	12 (5.9%)
Stroke	<5	11 (5.4%)
Other cardiovascular disease	<5	11 (5.4%)
Other respiratory condition	<5	9 (4.4%)
Other infection	5 (8.8%)	6 (2.9%)
Cerebral palsy	<5	11 (5.4%)
Dementia	9 (15.8%)	<5
Other gastrointestinal disorders	<5	8 (3.9%)
Ulcer/gastrointestinal perforation	<5	7 (3.4%)
Diabetes	<5	7 (3.4%)
Other congenital condition	<5	6 (2.9%)
Other ischaemic heart condition	<5	6 (2.9)
Mental health	<5	<5
Other neurological conditions	<5	<5
Renal failure	<5	<5
All deaths	57 (100%)	205 (100%)