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. 2020 May 20;2(7):e428–e436. doi: 10.1016/S2665-9913(20)30120-X

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Potential mechanisms of action for DMARDs in COVID-19

DMARDs could target different stages of the virus infection and immune activation. AT2=alveolar type 2. DMARDs=disease modifying anti-rheumatic drugs. GM-CSF= granulocyte-macrophage colony stimulating factor. IFNγ= interferon gamma. IL=interleukin. IP-10=interferon gamma-induced protein 10. MCP-1=monocyte chemoattractant protein-1. SARS-CoV-2=severe respiratory syndrome coronavirus 2. TNFα=tumor necrosis factor alpha.