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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Pain Symptom Manage. 2020 Jan 8;59(6):1248–1259.e5. doi: 10.1016/j.jpainsymman.2019.12.352

Table 3.

Multiple Logistic Regression Analyses Predicting Nausea Group Membership

Sample 1 (n = 334)

Predictor Odds Ratio 95% CI p-value

Karnofsky Performance Status score 0.95 0.93, 0.97 < 0.001

CTX cycle length 0.023
 21 day cycle vs 14 day cycle 0.50 0.31, 0.83 0.007
 28 day cycle vs 14 day cycle 0.87 0.34, 2.27 0.780
 21 day cycle vs 28 day cycle 0.58 0.22, 1.50 0.256

Type of prior cancer treatment 0.031
 Only surgery, CTX, or RT vs No prior treatment 0.95 0.53, 1.71 0.860
 Surgery & CTX, or Surgery & RT, or CTX & RT vs No prior treatment 0.38 0.19, 0.78 0.009
 Surgery & CTX & RT vs No prior treatment 0.93 0.39, 2.18 0.861
 Surgery & CTX, or Surgery & RT, or CTX & RT vs Only surgery, CTX, or RT 0.40 0.21, 0.78 0.007
 Surgery & CTX & RT vs Only surgery, CTX, or RT 0.98 0.43, 2.20 0.955
 Surgery & CTX, or Surgery & RT, or CTX & RT vs Surgery & CTX & RT 0.41 0.17, 1.00 0.050

Overall model fit: df = 6, X2 = 43.46, p < 0.001

Sample 2 (n = 294)

Predictor Odds Ratio 95% CI p-value

Child care responsibilities 1.90 1.05, 3.42 0.033

Karnofsky Performance Status score 0.96 0.94, 0.98 < 0.001

Emetogenicity of CTX 0.016
 Moderate vs Minimal/Low 1.60 0.82, 3.11 0.166
 High vs Minimal/Low 3.40 1.47, 7.85 0.004
 Moderate vs High 0.47 0.23, 0.97 0.041

Cancer diagnosis 0.003
 Gastrointestinal cancer vs Breast cancer 1.76 0.90, 3.46 0.099
 Gynecological cancer vs Breast cancer 0.64 0.32, 1.28 0.207
 Lung cancer vs Breast cancer 0.35 0.15, 0.84 0.019
 Gastrointestinal cancer vs Lung cancer 5.00 1.94, 12.91 0.001
 Gynecological cancer vs Lung cancer 1.81 0.70, 4.71 0.225
 Gynecological cancer vs Gastrointestinal cancer 0.36 0.18, 0.75 0.006

Overall model fit: df = 7, X2 = 48.34, p < 0.001

Abbreviations: CI = confidence interval, CTX = chemotherapy, RT = radiotherapy