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. Author manuscript; available in PMC: 2021 May 18.
Published in final edited form as: Curr Biol. 2020 Apr 2;30(10):1916–1926.e3. doi: 10.1016/j.cub.2020.03.033

Figure 7. Age-dependent deficits in visual behaviors after cone degeneration.

Figure 7.

(A) Schematic of the experimental setup for optokinetic testing. Drifting square-wave gratings (temporalnasal) were presented on a monitor 16 cm in front of the left eye. Movements of the left eye were recorded under IR illumination via a hot mirror.

(B, F) Representative eye movement traces for control (top) and Cone-DTR (bottom) mice 30 days after DT injection at P10 (B) and P30 (F).

(C, G) Summary data for eye tracking movements (ETMs) in control (open) and Cone-DTR (filled) mice 30 days after DT injection at P10 (C) and P30 (G).

(D) Illustration of the setup for visual cliff testing as described in STAR Methods.

(E, H) Summary data for percentage of shallow-side choices in control (open) and Cone-DTR (filled) mice 30 days after DT injection at P10 (E) and P30 (H). Throughout this figure, absence of an asterisk indicates p ≥ 0.05, * indicates p < 0.05, ** indicates p < 0.01, and *** indicates p < 0.001. See also Table S6.