Table 3.
Pearson correlation analysis between aggregated brain activation (contrast “alcohol vs. neutral/scramble, incongruent vs. congruent”) and symptom load in ROIs with significant interaction effects between AUD and ADHD severity. A: Median split into low/high ADS; correlation with ADHD severity. B: Median split into low/high ADHD; correlation with AUD severity
| A | ROI |
Low ADS (‘impulsivity’) corr. Coeff./ sign |
High ADS (‘impulsivity’) corr. Coeff./ sign |
Low ADS (‘overall’) corr. Coeff./ sign |
High ADS (‘overall’) corr. Coeff./ sign |
|---|---|---|---|---|---|
| Right middle frontal gyrus | −0.428/ .033 | 0.359/ .085 | −0.349/ .088 | 0.384/ .064 | |
| Right thalamus | −0.683/ .000 | 0.178/ .404 | −0.509/ .009 | 0.261/ .217 | |
| Right middle temporal gyrus | −0.642/ .001 | 0.364/ .080 | −0.604/ .001 | 0.406/ .049 | |
| Right BA10 | −0.458/ .021 | 0.384/ .064 | −0.341/ .095 | 0.382/ .066 | |
| Right insula | −0.486/ .014 | 0.429/ .037 | −0.431/ .031 | 0.447/ .028 | |
| Left lingual gyrus | −0.537/ .006 | 0.252/ .235 | −0.333/ .104 | 0.290/ .170 | |
| Right lingual gyrus | −0.566/ .003 | 0.235/ .268 | −0.354/ .083 | 0.275/ .193 | |
| Right lingual gyrus | −0.549/ .004 | 0.335/ .110 | −0.510/ .009 | 0.338/ .106 | |
| Right superior frontal gyrus | −0.462/ .020 | 0.362/ .082 | −0.380/ .061 | 0.380/ .067 | |
| Right inferior frontal gyrus | −0.575/ .003 | 0.218/ .307 | −0.454/ .023 | 0.321/ .126 | |
| Right pallidum | −0.586/ .002 | 0.418/ .042 | −0.553/ .004 | 0.430/ .036 | |
| Right putamen | −0.568/ .003 | 0.503/ .012 | −0.481/ .015 | 0.525/ .008 | |
| B | ROI |
Low ADHD (‘impulsivity’) corr. Coeff./ sign |
High ADHD (‘impulsivity’) corr. Coeff./ sign |
Low ADHD (‘overall’) corr. Coeff./ sign |
High ADHD (‘overall’) corr. Coeff./ sign |
| Right middle frontal gyrus | −0.690/ .000 | 0.161/ .451 | −0.685/ .000 | 0.274/ .196 | |
| Right thalamus | −0.515/ .008 | 0.248/ .244 | −0.473/ .017 | 0.231/ .278 | |
| Right middle temporal gyrus | −0.714/ .000 | 0.279/ .187 | −0.680/ .000 | 0.303/ .150 | |
| Right BA10 | −0.670/ .000 | 0.233/ .272 | −0.641/ .001 | 0.301/ .153 | |
| Right insula | −.0.386/ .057 | 0.410/ .047 | −0.346/ .090 | 0.396/ .055 | |
| Left lingual gyrus | −0.526/ .007 | 0.363/ .082 | −0.506/ .010 | 0.395/ .056 | |
| Right lingual gyrus | −0.479/ .016 | 0.304/ .149 | −0.462/ .020 | 0.319/ .129 | |
| Right lingual gyrus | −0.511/ .009 | 0.493/ .014 | −0.476/ .016 | 0.483/ .017 | |
| Right superior frontal gyrus | −0.695/ .000 | 0.184/ .388 | −0.687/ .000 | 0.284/ .179 | |
| Right inferior frontal gyrus | −0.351/ .085 | 0.391/ .059 | −0.385/ .058 | 0.442/ .031 | |
| Right pallidum | −0.462/ .020 | 0.312/ .138 | −0.515/ .008 | 0.398/ .054 | |
| Right putamen | −0.272/ .189 | 0.289/ .171 | −0.316/ .124 | 0.360/ .084 |