Table 2.
Factors significantly different between patients and controls
| Name | Uniprot | Ratio | FDR | VIP | |
|---|---|---|---|---|---|
| EGFR | Epidermal growth factor receptor | P00533 | 0.3 | < 0.001 | 2.6 |
| NT pro-BNP | N-terminal prohormone brain natriuretic peptide | 569 | < 0.001 | 2.5 | |
| PON3 | Paraoxonase (PON3) | Q15166 | 0.1 | < 0.001 | 2.6 |
| TLT-2 | Trem-like transcript 2 protein | Q5T2D2 | 0.2 | < 0.001 | 1.9 |
| TFPI | Tissue factor pathway inhibitor | P10646 | 0.3 | < 0.001 | 1.9 |
| GDF-15 | Growth/differentiation factor 15 | Q99988 | 10.3 | < 0.001 | 2.0 |
| PAI | Plasminogen activator inhibitor 1 | P05121 | 0.1 | < 0.001 | 1.2 |
| U-PAR | Urokinase plasminogen activator surface receptor | Q03405 | 3.2 | < 0.001 | 1.5 |
| MMP-3 | Matrix metalloproteinase-3 | P08254 | 4 | 0.001 | 1.5 |
| SELP | P-selectin | P16109 | 0.2 | 0.001 | 1.2 |
| FABP4 | Fatty acid-binding protein, adipocyte | P15090 | 10.2 | 0.001 | 1.5 |
| CNTN1 | Contactin-1 | Q12860 | 0.5 | 0.001 | 1.5 |
| TR-AP | Tartrate-resistant acid phosphatase type 5 | P13686 | 0.4 | 0.002 | 1.7 |
| PDGF subunit-A | Platelet-derived growth factor subunit A | P04085 | 0.1 | 0.002 | 1.2 |
| SPON1 | Spondin-1 | Q9HCB6 | 2.6 | 0.002 | 1.3 |
| DLK-1 | Protein delta homolog 1 | P80370 | 0.3 | 0.003 | 1.4 |
| ITGB2 | Integrin beta-2 | P05107 | 0.4 | 0.003 | 1.2 |
| PI3 | Elafin | P19957 | 4.2 | 0.003 | 1.2 |
| LDL-receptor | Low-density lipoprotein receptor | P01130 | 0.3 | 0.003 | 1.3 |
| Gal-4 | Galectin-4 | P56470 | 2.5 | 0.004 | 1.6 |
| ST2 | ST2 protein | Q01638 | 3.3 | 0.005 | 1.4 |
| COL1A1 | Collagen alpha-1(I) chain | P02452 | 0.4 | 0.005 | 1.4 |
| CASP-3 | Caspase-3 | P42574 | 0.1 | 0.006 | 0.9 |
| OPN | Osteopontin | P10451 | 2.9 | 0.007 | 1.2 |
| BLM hydrolase | Bleomycin hydrolase | Q13867 | 0.5 | 0.008 | 1.1 |
| TFF3 | Trefoil factor 3 | Q07654 | 3.1 | 0.008 | 1.1 |
| TR | Transferrin receptor protein 1 | P02786 | 3.3 | 0.008 | 1.3 |
| PLC | Perlecan | P98160 | 2.1 | 0.009 | 1.2 |
| CSTB | Cystatin-B | P04080 | 3.2 | 0.010 | 1.1 |
| IGFBP-7 | Insulin-like growth factor-binding protein 7 | Q16270 | 3.2 | 0.011 | 1.2 |
| TNF-R1 | Tumor necrosis factor receptor 1 | P19438 | 2.7 | 0.012 | 1.1 |
| PECAM-1 | Platelet endothelial cell adhesion molecule | P16284 | 0.3 | 0.019 | 0.7 |
| TNF-R2 | Tumor necrosis factor receptor 2 | P20333 | 2.4 | 0.020 | 0.9 |
| FAS | Tumor necrosis factor receptor superfamily member 6 | P25445 | 0.6 | 0.021 | 1.0 |
| MPO | Myeloperoxidase | P05164 | 0.5 | 0.026 | 0.9 |
| PSP-D | Pulmonary surfactant-associated protein D | P35247 | 2.8 | 0.026 | 1.0 |
| Ep-CAM | Epithelial cell adhesion molecule | P16422 | 0.3 | 0.030 | 0.9 |
| CCL24 | C–C motif chemokine 24 | O00175 | 0.3 | 0.037 | 1.0 |
| RARRES2 | Retinoic acid receptor responder protein 2 | Q99969 | 0.6 | 0.037 | 0.9 |
Uniprot uniprot accession, Ratio The ration between patients vs controls. FDR false discovery rate for parametric groupwise comparison. VIP variable importance in projection from OPLA-DA classification