Table 2.
Regression analysis of potential risk factors for severe postoperative complications (Dindo-Clavien ≥ 3)
| Risk factor | n | Complication rate | versus | n | Complication rate | p value | OR (95% CI) |
|---|---|---|---|---|---|---|---|
| Duodenopancreatic primary tumor | 131 | 22% | Small intestinal primary tumor | 133 | 11% | 0.014 | 2.20 (1.13–4.29) |
| Duodenopancreatic primary tumor | 131 | 22% | All non-duodenopancreatic tumors | 245 | 10% | 0.003 | 2.38 (1.34–4.23) |
| Curative resection of lymph node metastases | 112 | 21% | No Lymph node metastases or palliative aim of resection | 264 | 12% | 0.020 | 1.99 (1.11–3.56) |
| Functioning tumor | 87 | 23% | Non-functioning tumors | 222 | 13% | 0.042 | 1.91 (1.02–3.59) |
| NET/NEC G3 | 35 | 11% | NET G1, NET G2 | 321 | 16% | 0.505 | 0.69 (0.17–2.09) |
| Age ≥ 60 years | 221 | 14% | Age < 60 years | 155 | 16% | 0.573 | 0.85 (0.46–1.57) |
| Cardiovascular disease | 112 | 12% | No cardiovascular disease | 264 | 16% | 0.249 | 0.68 (0.32–1.36) |
| BMI ≥ 30 kg/m2 | 59 | 24% | BMI < 30 kg/m2 | 193 | 15% | 0.120 | 1.76 (0.79–3.78) |
| Men | 166 | 17% | Women | 210 | 13% | 0.330 | 0.75 (0.41–1.39) |
OR odds ratio; CI confidence interval; NET neuroendocrine tumor; NEC neuroendocrine carcinoma; BMI body mass index