Table 2.
Performance of the automated head-twitch response (HTR) detection after optimization of the preprocessing procedures.
Experiment | Drug | Age (weeks) | Duration (min) | N | Manual HTR counts | Automated HTR counts | Percent detecteda | False positive detections | Total errorsb | Total error ratec | R value |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | LSD | 23 | 30 | 24 | 1,311 | 1,304 | 99.47% | 2 | 9 | 0.69% | 0.9995 |
2 | 25I-NBOMe | 20 | 30 | 25 | 1,472 | 1,472 | 100.00% | 12 | 12 | 0.82% | 0.9994 |
3 | 2C-I | 30 | 30 | 27 | 1,388 | 1,381 | 99.50% | 5 | 12 | 0.86% | 0.9998 |
4 | 25I-NBMD | 45 | 20 | 13 | 297 | 292 | 98.32% | 0 | 5 | 1.68% | 0.9988 |
5 | 1-Butanoyl-LSD | 18 | 30 | 31 | 975 | 972 | 99.69% | 15 | 18 | 1.85% | 0.9987 |
6 | DOB-FLY | 36 | 30 | 23 | 1,771 | 1,763 | 99.55% | 14 | 22 | 1.24% | 0.9997 |
7 | R-(–)-DOI | 34 | 30 | 8 | 633 | 629 | 99.37% | 2 | 6 | 0.95% | 0.9997 |
8 | Mescaline | 37 | 30 | 27 | 855 | 852 | 99.65% | 2 | 5 | 0.58% | 0.9999 |
9 | DOB | 20 | 30 | 33 | 1,819 | 1,791 | 98.46% | 17 | 45 | 2.47% | 0.9991 |
10 | Psilocybin | 30 | 30 | 16 | 403 | 401 | 99.50% | 6 | 8 | 1.99% | 0.9991 |
11 | 2C-T-7 | 25 | 30 | 10 | 388 | 387 | 99.74% | 5 | 6 | 1.55% | 0.9994 |
Totals: | 237 | 11,312 | 11,244 | 99.40% | 80 | 148 | 1.31% |
a Percent detected = (automated HTR count ÷ manual HTR count) × 100.
bTotal errors = number of false positive detections + number of head twitches that were detected manually but not by the automated procedures.
cTotal error rate = total errors ÷ manual HTR count.