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. 2020 May 20;10:8344. doi: 10.1038/s41598-020-65264-x

Table 2.

Performance of the automated head-twitch response (HTR) detection after optimization of the preprocessing procedures.

Experiment Drug Age (weeks) Duration (min) N Manual HTR counts Automated HTR counts Percent detecteda False positive detections Total errorsb Total error ratec R value
1 LSD 23 30 24 1,311 1,304 99.47% 2 9 0.69% 0.9995
2 25I-NBOMe 20 30 25 1,472 1,472 100.00% 12 12 0.82% 0.9994
3 2C-I 30 30 27 1,388 1,381 99.50% 5 12 0.86% 0.9998
4 25I-NBMD 45 20 13 297 292 98.32% 0 5 1.68% 0.9988
5 1-Butanoyl-LSD 18 30 31 975 972 99.69% 15 18 1.85% 0.9987
6 DOB-FLY 36 30 23 1,771 1,763 99.55% 14 22 1.24% 0.9997
7 R-(–)-DOI 34 30 8 633 629 99.37% 2 6 0.95% 0.9997
8 Mescaline 37 30 27 855 852 99.65% 2 5 0.58% 0.9999
9 DOB 20 30 33 1,819 1,791 98.46% 17 45 2.47% 0.9991
10 Psilocybin 30 30 16 403 401 99.50% 6 8 1.99% 0.9991
11 2C-T-7 25 30 10 388 387 99.74% 5 6 1.55% 0.9994
Totals: 237 11,312 11,244 99.40% 80 148 1.31%

a Percent detected = (automated HTR count ÷ manual HTR count) × 100.

bTotal errors = number of false positive detections + number of head twitches that were detected manually but not by the automated procedures.

cTotal error rate = total errors ÷ manual HTR count.