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. 2020 Apr 9;124(6):751–762. doi: 10.1038/s41437-020-0311-2

Table 2.

Total narrow-sense heritability estimates for real phenotypes under the KIBD & KIBD & age & sex & 10 PCs model using (i) GCTA; (ii) GCTA followed byPCA-based rescaling; and (iii) LDAK with an optimal trait-specific parameter α and LD weighting, as well as comparison with (iv) published totalheritability estimates in Europeans and Mexicans.

GCTA estimate (mean ± s.e.) Rescaled GCTA point estimate Best LDAK estimate (mean ± s.e.) Estimate from the literature (mean ± s.e.)
Height 0.656 ± 0.042 0.611 0.786 ± 0.041 0.860 ± 0.117 (Visscher et al. 2007)
Weight 0.533 ± 0.044 0.504 0.536 ± 0.049 0.630 (Mamtani et al. 2014)
Body mass index 0.505 ± 0.045 0.494 0.470 ± 0.05 0.340 ± 0.120 (Vattikuti et al. 2012)
Hip circumference 0.494 ± 0.046 0.472 0.534 ± 0.05 0.680 (Mamtani et al. 2014)
Waist circumference 0.464 ± 0.047 0.461 0.479 ± 0.051 0.620 (Mamtani et al. 2014)
Waist-to-hip ratio 0.352 ± 0.050 0.348 0.385 ± 0.054 0.280 ± 0.120 (Vattikuti et al. 2012)
Total cholesterol 0.487 ± 0.047 0.475 0.523 ± 0.05 0.510 (van Dongen et al. 2013)
HDL cholesterol 0.453 ± 0.046 0.431 0.512 ± 0.049 0.480 ± 0.110 (Vattikuti et al. 2012)
LDL cholesterol 0.497 ± 0.050 0.496 0.534 ± 0.052 0.510 (van Dongen et al. 2013)
Triglycerides 0.312 ± 0.051 0.308 0.333 ± 0.054 0.470 ± 0.120 (Vattikuti et al. 2012)