Table 1.
Baseline characteristics of the 42 subjects in the cohort.
| Parameter | Controls N = 12 | Prediabetes N = 16 | T2D N = 14 | p |
|---|---|---|---|---|
| Age | 60 ± 6 | 64 ± 6 | 62 ± 7 | 0.234 |
| BMI | 30.1 ± 4.7 | 30.4 ± 3.7 | 30.3 ± 3.6 | 0.852 |
| Sex | 6F/6M | 9F/7M | 6F/8M | — |
| WHR | 0.93 ± 0.10 | 1.00 ± 0.09 | 1.01 ± 0.04 | 0.061 |
| HbA1c | 34.2 ± 2.6 | 36.9 ± 3.1 | 55.1 ± 12.1 | 0.000 |
| OGTT AUCglucose | 819.8 ± 138.2 | 1073.1 ± 178.8 | 1731.9 ± 393.5 | 0.000 |
| HOMA-IR | 1.9 ± 1.1 | 2.8 ± 1.5 | 5.1 ± 2.7 | 0.003 |
| M-value | 10.2 ± 2.9 | 8.0 ± 3.8 | 5.3 ± 2.5 | 0.002 |
The mean value and the standard deviation are shown for anthropometric and diabetes metabolic markers. The following units were used: age (years), BMI (kg/m2), sex (proportion of females (F) and males (M)), WHR (ratio of waist- to hip circumference), HbA1c (mmol/mol), OGTT AUCglucose (mmol/L*min) and M-value (mg/kg LBM/min). Statistical significance among controls, prediabetes and T2D for the baseline characteristics was calculated from a Kruskal-Wallis rank sum test.