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. 2020 May 20;10:8358. doi: 10.1038/s41598-020-65253-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Polyphenols and clindamycin modulated microbiota in distinct ways. a Dendrogram presentation of Bray-Curtis dissimilarities with the bar-plot presentation of the relative abundance of 3 dominant bacterial phyla. Sample names are colored according to polyphenol extract (PE), that was used during the modulation phase. Green indicates control treatment, blue exposure to blueberry PE and orange exposure to pomegranate PE. Abbreviation “Cli” indicates exposure to clindamycin. b LEfSE analysis showing the comparison between communities exposed to either PE, clindamycin or combination of both compared to the control treatment. LDA values are presented as heat-plot with red indicating a decrease of specific OTU while blue an increase. Letter before OTU taxonomy indicates taxonomic level: g - genus, f - family, o - order, p - phylum. c Box presentation of the number of unique OTUs and Shannon evenness according to the treatment.