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. 2020 May 14;11:298. doi: 10.3389/fendo.2020.00298

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Copyright © 2020 He, Zhu, Yang, Li, Huang, Shen, Liu and Zha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ratios of Th17 cells decreased progressively with increased TSH concentration in pregnant women during the second trimester. Representative staining of CD4lymphocytes for intracellular IL-17A in pregnant women with TSH levels ≤ 2.5 mIU/L (n = 26), >2.5 mIU/L (n = 26) (A), ≤ 4 mIU/L (n = 20), and >4 mIU/L (n = 20) (B). The percentages of CD4⁺ T cells expressing IL-17A are shown as individual dots for the two groups. The significance levels of differences between the groups in each subset were analyzed using the t-test (**P < 0.001).