Table 3.

Multivariable Cox regression analysis of the independent prognostic factors for OS and DSS among primary hepatic lymphoma patients.

Variables	Overall survival			Disease-specific survival
	HR	95% CI	P	HR	95% CI	P
Age at diagnosis, years
0–29	Reference			Reference
30–49	1.24	0.77–1.97	0.371	1.42	0.84–2.41	0.187
50–69	1.78	1.12–2.81	0.014	1.81	1.07–3.05	0.025
≥70	2.96	1.88–4.68	<0.001	3.04	1.81–5.09	<0.001
Sex
Female	Reference			Reference
Male	1.46	1.24–1.71	<0.001	1.44	1.19–1.72	<0.001
Race
Black	Reference			Reference
White	0.76	0.60–0.96	0.019	0.75	0.58–0.96	0.025
Othersa	1.08	0.77–1.51	0.642	1.11	0.77–1.59	0.589
Years of diagnosis
1983–1993	Reference			Reference
1994–2004	0.67	0.52–0.87	0.002	0.59	0.45–0.79	<0.001
2005–2015	0.56	0.43–0.73	<0.001	0.48	0.36–0.64	<0.001
Marital status
Married	Reference			Reference
Unmarried	1.41	1.21–1.64	<0.001	1.49	1.26–1.78	<0.001
Classification
Hodgkin Lymphoma	Reference			Reference
Aggressive B cell NHL	1.12	0.69–1.80	0.634	1.28	0.72–2.28	0.397
Indolent B cell NHL	0.78	0.47–1.31	0.359	0.88	0.47–1.64	0.709
NHL-NOS	0.93	0.55–1.56	0.782	1.06	0.57–1.99	0.836
T cell NHL	2.22	1.22–4.03	0.009	2.75	1.38–5.51	0.004
Other/unclassified	0.98	0.58–1.66	0.933	1.04	0.55–1.97	0.895
Surgery
No/unknown	Reference			Reference
Performed	0.74	0.58–0.94	0.02	0.60	0.42–0.86	0.008
Radiation
No/unknown	Reference			Reference
Performed	1.15	0.83–1.59	0.406	1.05	0.72–1.54	0.774
Chemotherapy
No/unknown	Reference			Reference
Performed	0.45	0.39–0.53	<0.001	0.43	0.36–0.51	<0.001

^aAmerican Indian/Alaskan Native or Asian/Pacific Islander.