Table 1.
Baseline and procedural characteristics of the present prospective cohort.
| Prospective cohort n = 166 | IABP-Shock II (score cohort) n = 480 | Card-Shock ACS n = 137 | |
|---|---|---|---|
| Age, mean (SD), years | 65 ± 12 | 70 [58–77] | 68 [61–76] |
| Gender- male, n (%) | 137 (82.5) | 331 (69) | 106 (77) |
| Height, mean (SD), cm | 173 ± 12 | 174 [167–180] | 171 [165–176] |
| Weight, mean (SD), [kg] | 81 ± 17 | 80 [73–90] | 78 [70–85] |
| BMI, mean (SD), kg/m2 | 27 ± 4 | 27 [25-30] | 26.8 [24-27] |
| IABP Shock II Score, median (IQR) | 3 [2-4] | 3 | 2 |
| 0–2, low-risk, n (%) | 72 (43) | 235 (49) | 81 (59) |
| 3–4, intermediate-risk, n (%) | 79 (48) | 181 (38) | 35 (26) |
| 5–9, high-risk, n (%) | 15 (9) | 64 (13) | 21 (15) |
| CardShock Score, median (IQR) | 5 [4-6] | ||
| 0–3, low-risk, n (%) | 19 (11) | ||
| 4–5, intermediate-risk, n (%) | 72 (44) | ||
| 6–9, high-risk, n (%) | 75 (45) | ||
| Admission lactate, mean (SD), mmol/L | 6.8 ± 0.5 | 3.7 [2.1–7.3] | 4.3 [1.8–5.2] |
| Pre-existing conditions | |||
| Hypertension, n (%) | 100 (60) | 341/477 (35) | 81 (42) |
| Diabetes mellitus, n (%) | 45 (27) | 162/478 (34) | 39 (29) |
| Hyperlipidaemia, n (%) | 63 (38) | 201/476 (42) | 64 (47) |
| Smoking, n (%) | 81 (49) | 165/475 (35) | 58 (42) |
| CKD, n (%) | 25 (15) | – | – |
| LV-EF, mean (SD), % | 21± 10 | 35 | – |
| Cardiac arrest prior to Impella, n (%) | 65 (39) | 209/480 (44) | 39 (29) |
| ROSC, mean (SD), min | 20 ± 16 | – | – |
| Infarct location, n (%) | |||
| Left main | 43 (26) | 9% | |
| LAD | 78 (47) | 43% | |
| LCX | 17 (10) | 17% | |
| RCA | 25 (15) | 26% | |
| Bypass graft | 3 (2) | 3% | |
| Revascularisation, n (%) | |||
| None | 8 (5) | 0% | 0% |
| PCI | 156 (94) | 100% | 100% |
| CABG | 2 (1) | 0% | 0% |
| TIMI flow at the end of procedure | |||
| TIMI 0/I | 13 (8) | ||
| TIMI II | 15 (9) | ||
| TIMI III | 138 (83) | 295 (82) | 98 (72) |
| Bridge to durable LVAD | 3 (2) | ||
BMI, body mass index; CABG, coronary artery bypass graft; CKD, chronic kidney disease; LAD, left anterior descending coronary artery; LCX, left circumflex coronary artery; LVAD, left ventricular assist device; LV-EF, left-ventricular ejection fraction; PCI, percutaneous coronary intervention; RCA, right coronary artery; ROSC, Return of spontaneous circulation; SAPS II, Simplified Acute Physiology Score-II; TIMI, thrombolysis in myocardial infarction.