TABLE 1.

Comparison of the biological activities of E. coli-expressed SAA1 before (SAA1) and after (hrSAA1) purification to homogeneity using RP-HPLC.

Activity	SAA1	hrSAA1
In vivo mononuclear cell attraction	x	x
In vivo neutrophil attraction	x	x
Synergy with CXCL8 in neutrophil migration	x	x
Desensitization of FPR2-mediated calcium signaling by CCL23(46−137)	x	x
Induction of MMP-9 release in monocytes	x	–
Induction of chemokine expression in monocytes	x	–
Induction of ROS production in monocytes	x	–
Monocyte survival	x	x
Macrophage polarization	x	–

x, biological activity demonstrated; – not active.