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. 2020 May 14;8:315. doi: 10.3389/fcell.2020.00315

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Copyright © 2020 Marconi, Diomede, Pizzicannella, Fonticoli, Merciaro, Pierdomenico, Mazzon, Piattelli and Trubiani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Graph bar of RT-PCR showed the mRNA levels of VEGF and RUNX2 in cells seeded on CTRL and TEST surface after 8 weeks of culture ** p < 0.01. (B) Protein level expression of VEGF and RUNX2 in cells seeded on CTRL and TEST surface after 8 weeks of culture. (C) Graphs evidence densitometric analysis of protein bands expressed as integrated optical intensity (IOI) average of three separate experiments. The error bars on these graphs showed standard deviation (±SD). Densitometric values evaluated by ANOVA return significant differences, ** p < 0.01.