TABLE 1.
Echocardiographic analyses of diastolic and systolic diameters from left ventricle of T. cruzi-infected CD-1 mice at 90 dpia
| Parameter | Value for the following group: |
||
|---|---|---|---|
| U | I | +RvD1 | |
| Body wt (g) | 45.94 ± 1.28 | 42.84 ± 2.63 | 36.44 ± 2.22#,* |
| Heart rate (no. of beats/min) | 528.8 ± 52.25 | 465 ± 82.1 | 490.4 ± 87.27 |
| Ejection fraction (%) | 57.56 ± 6.81 | 56.52 ± 8.3 | 69.89 ± 11.12 |
| Fractional shortening (%) | 30.65 ± 6.67 | 29.71 ± 5.3 | 35.97 ± 4.786 |
| LV mass (g) | 121.7 ± 31.54 | 173.4 ± 36.4 | 118.7 ± 29.12# |
| LVIDd (mm) | 4.3 ± 0.37 | 4.7 ± 0.20 | 4.1 ± 0.60 |
| LVIDs (mm) | 3.0 ± 0.3 | 3.2 ± 0.4 | 2.8 ± 0.4 |
| RWT (mm) | 0.40 ± 0.06 | 0.31 ± 0.05 | 0.38 ± 0.12 |
a
U, uninfected; I, infected; +RvD1, infected and treated with RvD1 during chronic infection; LVIDs, left ventricular systolic inner dimension. *, significant differences (P < 0.05) in comparison to the uninfected control; #, significant differences (P < 0.05) in comparison to the infected controls. P values were determined by one-way ANOVA with Tukey’s posttest.