TABLE 2.

Metabolites identified as significantly different in abundance between C. burnetii eirA::Tn mutant and WT strains using LC-MS

Metabolite	Fold changea	BH-adjusted P valueb
l-Asp	0.62	3.56 × 10−3
l-Glu	0.70	2.55 × 10−5
l-Leu	0.38	2.42 × 10−2
l-Ser	0.59	1.60 × 10−3
l-Met	0.43	1.04 × 10−3
l-Lys	1.04	9.28 × 10−3
l-Tyr	0.24	1.19 × 10−2
3′-Methyladenine	0.57	1.55 × 10−2
meso-2,6-diaminopimelate	0.86	3.43 × 10−3
GDP-d-mannose	−0.32	1.55 × 10−2
UDP-GlcNAc	−0.37	1.41 × 10−2
NADH	0.33	3.67 × 10−2
NADP	−0.50	1.22 × 10−2

^aPositive fold change values denote metabolites with significantly higher abundance, while negative fold change value denote metabolites with significantly lower abundance in C. burnetii eirA::Tn mutant than in the WT.

^bBH, Benjamini-Hochberg.