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. 2020 May 14;11:681. doi: 10.3389/fphar.2020.00681
Variables TTS
(n=103)
ACS
(n=422)
p value*
Drugs on admission. n (%)
 Beta-blocker 41 (41.8) 133 (31.8) 0.06
 ACE inhibitor 42 (42.9) 106 (25.2) <0.01
 Aldosterone inhibitor 1 (1.0) 2 (0.5) 0.52
 Aspirin 31 (31.6) 117 (27.9) 0.56
 Therapeutic anticoagulation 10 (10.3) 24 (5.7) 0.10
Drugs on discharge. n (%)
 Beta-blocker 103 (100.0) 422 (100.0)
 ACE inhibitor 67 (65.0) 316 (74.9) 0.04
 Aldosterone inhibitor 2 (1.9) 5 (1.2) 0.55
 Aspirin 47 (45.6) 414 (98.1) <0.01
 Clopidogrel 7 (6.8) 372 (88.2) <0.01
 Aspirin + clopidogrel 7 (6.8) 369 (87.4) <0.01
 Cumarine 10 (9.7) 10 (2.4) <0.01
 Heparin 16 (15.5) 25 (5.9) 0.01
 Factor Xa inhibitors 5 (4.9) 0 (0) <0.01

*p values for the comparison between TTS and ACS.

ACE, angiotensin-converting-enzyme; ACS, acute coronary syndrome; BMI, body-mass-index; BP, blood pressure; COPD, chronic obstructive pulmonary disease; ECG, electrocardiogram; EF, ejection fraction; IQR, inter quartile range; LVEF, left ventricular ejection fraction; SD, standard deviation; TTS, Takotsubo syndrome.