Table 4.

Clinical trials investigating miRNA modulators.

MiRNA	Clinical setting	Reference
Anti-miR-21 treatment	Treatment of Alport nephropathy	Tapparo et al., 2019
Anti-miR-122 treatment	Treatment of hepatitis C virus infection	Chen et al., 2016
Mimic for miR-34 (MRX34)	tumor suppressor in a variety of cancers was evaluated in a phase 1 clinical trial on liver-based cancers	Song et al., 2018
Anti-miR-17 treatment (RGLS4326)	potential treatment for adult polycystic kidney disease	Zhang and Shu, 2016