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. Author manuscript; available in PMC: 2020 Jun 1.

Published in final edited form as: Am J Cardiol. 2019 Sep 6;124(11):1701–1706. doi: 10.1016/j.amjcard.2019.08.028

Table 2.

Predicted 10-year ASCVD risk and observed ASCVD events by primary and secondary prevention populations and risk category

Population and risk category	n ASCVD events/N (%)	IR/1,000 P-Y (95% CI)	HR for ASCVD events (95% CI)	HR for ASCVD events
(95% CI)^*	HR for ASCVD events (95% CI)
Primary prevention	212/6,874 (3.1%)	9.6 (8.3, 10.9)	Ref	–
10-year risk <10%	27/1,503 (1.8%)	5.5 (3.8, 8.0)	–	Ref^a	Ref^x
10-year risk 10% to <20%	73/2,967 (2.5%)	7.5 (6.0, 9.5)	–	Ref^b	x: 1.36 (0.88, 2.12)
10-year risk 20% to <30%	70/1,529 (4.6%)	14.3 (11.3, 18.1)	–	Ref^c	x: 2.58 (1.65, 4.03)
10-year risk ≥30%	42/875 (4.8%)	15.8 (11.6,21.3)	–	Ref^d	x: 2.85 (1.76, 4.63)
Secondary prevention	93/1,277 (7.3%)	23.9 (19.5, 29.3)	2.51 (1.96,3.20)	–
10-year risk <10%	11/218 (5.0%)	16.4 (9.1,29.6)	–	a: 2.97 (1.47,5.99)	Ref^y
10-year risk 10% to <20%	27/469 (5.8%)	18.6 (12.7, 27.1)	–	b: 2.48 (1.60, 3.86)	y: 1.13 (0.56, 2.28)
10-year risk 20% to <30%	27/323 (8.4%)	28.0 (19.2, 40.8)	–	c: 1.94 (1.25, 3.04)	y: 1.70 (0.84, 3.43)
10-year risk ≥30%	28/267 (10.5%)	35.2 (24.3, 50.9)	–	d: 2.23 (1.38,3.59)	y: 2.14 (1.07, 4.30)

^*

p value assessing interaction of prior ASCVD event by predicted risk category was 0.04. IR is incidence rate. P-Y is person-years.